Late-stage clinical pharmaceutical company Cinclus Pharma Holding AB (STO:CINPHA) on Thursday announced a strategic partnership and licensing agreement with Zentiva, a pharmaceutical company based in the Czech Republic, for the commercialisation and manufacturing of linaprazan glurate across Europe, including all EEA member states, the UK and Switzerland.
The total value of the deal amounts to EUR220m, including an upfront payment of EUR13m and a EUR5m milestone payment expected in 2026. Cinclus Pharma will also receive tiered double-digit royalties on net sales in Europe, beginning in the high teens and exceeding 20% at upper tiers.
Linaprazan glurate is a next-generation potassium-competitive acid blocker developed to treat severe erosive gastroesophageal reflux disease. The company plans to initiate its first Phase III trial of the therapy in the third quarter of 2025.
The global addressable market for this condition includes approximately 19 million patients, with 10 million across Europe and the United States.
Cinclus Pharma signs EUR220m European commercialisation deal with Zentiva for acid reflux therapy
Sanofi to acquire Vigil Neuroscience for USD470m to expand Alzheimer's pipeline
Moderna withdraws application for flu-COVID combination vaccine pending additional efficacy data
Revalesio reports further analysis from Phase 2 RNS60 trial for acute ischemic stroke treatment
AnnJi reports positive Phase 1/2a results in Spinal and Bulbar Muscular Atrophy trial
Sarepta receives UK approval to continue dosing in ELEVIDYS ENVISION study
MSD expands clinical development of Orion's opevesostat to include women's cancers
Promontory Therapeutics reports successful FDA meeting after Phase 2 study of PT-112
Trevi Therapeutics reports additional results from Phase 2a RIVER trial of Haduvio
Accropeutics reports positive data from Phase 2 psoriasis treatment trial
NextCell Pharma partners with Fujifilm Irvine Scientific to deliver integrated MSC solutions
Lifecare files for first human trial of glucose monitoring implant, targeting CE-mark
EXACT Therapeutics reports strong Phase 1 results for ACTIVATE trial in colorectal liver metastases