Sebela Women's Health Inc, part of US pharmaceutical company Sebela Pharmaceuticals, announced on Wednesday that its MIUDELLA Hormone-Free Copper Intrauterine System (IUS) has been named to TIME's list of the best inventions of 2025.

Sebela says that MIUDELLA is the first hormone-free copper intrauterine device (IUD) in the US in over 40 years. It was approved by the US Food and Drug Administration in February 2025 for the prevention of pregnancy in females of reproductive potential for up to three years, and it is expected to be available to patients through trained healthcare providers in the US in the first half of 2026.

To compile this year's list, TIME solicited nominations from TIME editors and correspondents around the world through an online application process, paying special attention to growing fields -- such as health care and AI. It then evaluated each contender on several key factors, including originality, efficacy, ambition, and impact.