Therapy Areas: Oncology
BioLineRx signs collaboration agreement with GenFleet Therapeutics
29 June 2022 -

BioLineRx Ltd. (NASDAQ: BLRX) (TASE: BLRX), an Israel-based late clinical-stage biopharmaceutical company, announced on Tuesday that it has signed a collaboration agreement with GenFleet Therapeutics, a China-based immuno-oncology focused biopharmaceutical company.

The collaboration agreement has been signed to advance Motixafortide via a randomised Phase 2b clinical trial in pancreatic ductal adenocarcinoma (PDAC).

According to the terms of the contract, GenFleet will completely fund, design and implement a randomised Phase 2b clinical trial that will enrol around 200 first-line metastatic PDAC patients in China. The randomised controlled study is intended to assess the superiority of Motixafortide in combination with an anti-PD-1 and chemotherapy compared to chemotherapy alone, the current standard of care. BioLineRx is to provide Motixafortide, while GenFleet will supply the other study drugs for the trial. A Joint Development Committee will administer the trial oversight. If the product is approved, GenFleet will be eligible to receive low-to-mid-single digit tiered percentage royalties on future Motixafortide sales.

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