South Korea-based iNtRON Biotechnology (www.intodeworld.com) announced on Monday the identification of Prophage and (non-) ORF-Jamphage from the microbiome frequently observed in long-term Pancreatic cancer survivors.
This significant identification was achieved as part of the ongoing PHAGERIARUS(R) development project conducted by the New Drug Part of the company.
The PHAGERIARUS(R) development project is focused on acquiring bacteriophage-derived proteins that can serve as Immune Regulators (IR). The ultimate goal is to develop phage-based immunotherapeutics capable of treating a range of immune disorders including cancer.
The project is built on the research that bacteriophages not only act as essential factors for the survival and growth of bacteria, but also play a role in regulating the immune system. In addition to the ongoing efforts to secure diverse IR candidates, the project involves with comprehensive genomic and functional analysis of disease-associated microbiomes and bacteriophages. Additionally, the project aims to elucidate the Mode of Action (MoA) of IR-related proteins derived from bacteriophages.
Recognising the potential substantial role of these lysogenic phages in inducing immune responses within the body, iNtRON is actively securing genetic resources derived from Prophage/Jamphage.
Amneal announces launch of PEMRYDI RTU, a ready-to-use oncology injectable
Medivir and Vetbiolix report positive results from VBX-1000 Proof-of-Concept clinical study
Norgine submits first marketing authorisation application submissions for approval of eflornithine
Innovent Biologics names new Oncology CMO
UroGen's UGN-103 IND accepted by FDA for bladder cancer treatment
Innate Pharma advances Sanofi-developed NK cell engager to Phase 2 for blood cancer patients
Precision Epigenomics partners with TruDiagnostic
Portage Biotech expands evaluation of strategic alternatives
Stamford Pharmaceuticals starts locally advanced basal cell carcinoma (laBCC) trial of SP-002
Candel Therapeutics granted FDA Orphan Drug Designation for CAN-2409 in pancreatic cancer treatment
ELIAS Animal Health names new chief revenue officer
Innate Pharma reports preclinical efficacy of IPH45
Roche attains CE Mark for first companion diagnostic for HER2-low metastatic breast cancer
BioCity Biopharma's BC2027 Phase one study IND application receives US FDA approval