Therapy Areas: Hereditary Disorders
Arcturus Therapeutics Acquires Exclusive License to mRNA Manufacturing Technology from Alexion Pharmaceuticals
23 February 2021 - - US-based clinical-stage messenger RNA medicines company Arcturus Therapeutics Holdings Inc. (NASDAQ: ARCT) has acquired an exclusive license from Alexion Pharmaceuticals (NASDAQ: ALXN) to certain patent-pending inventions relating to nucleic acid purification technologies, the company said.

Since the company's inception in 2013, Arcturus has been building proprietary expertise related to the manufacture of RNA through technological innovation.

The licensed inventions enable larger scale and faster production of mRNA. The technology supports the company's efforts to optimize the highly efficient manufacture of mRNA therapeutic candidates with an increased purity profile.

This acquisition extends the substantial intellectual property portfolio already held by Arcturus for the manufacture of high purity pharmaceutical quality mRNA therapeutic candidates for a range of diseases.

Founded in 2013 and based in San Diego, California, Arcturus Therapeutics Holdings Inc. (NASDAQ: ARCT) is a clinical-stage mRNA medicines and vaccines company with enabling technologies: LUNAR lipid-mediated delivery, STARR mRNA Technology and mRNA drug substance along with drug product manufacturing expertise.

Arcturus' diverse pipeline of RNA therapeutic and vaccine candidates includes mRNA vaccine programs for SARS-CoV-2 (COVID-19) and Influenza, and other programs to potentially treat Ornithine Transcarbamylase Deficiency, and Cystic Fibrosis along with partnered programs including Glycogen Storage Disease Type 3, Hepatitis B Virus, and non-alcoholic steatohepatitis.

Arcturus' versatile RNA therapeutics platforms can be applied toward multiple types of nucleic acid medicines including messenger RNA, small interfering RNA, replicon RNA, antisense RNA, microRNA, DNA, and gene editing therapeutics.

Arcturus' technologies are covered by its extensive patent portfolio (209 patents and patent applications, issued in the US, Europe, Japan, China and other countries).

Arcturus' commitment to the development of novel RNA therapeutics has led to collaborations with Janssen Pharmaceuticals, Inc., part of the Janssen Pharmaceutical Companies of Johnson and Johnson (NYSE: JNJ), Ultragenyx Pharmaceutical, Inc., Takeda Pharmaceutical Company Ltd (OTC: TKPHF), CureVac AG (NASDAQ: CVAC), Synthetic Genomics Inc., Duke-NUS Medical School, and the Cystic Fibrosis Foundation.


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