Biopharmaceutical company Faron Pharmaceuticals Ltd (AIM: FARN) (First North: FARON) announced on Monday that it has filed a patent application for the use of soluble Clever-1 to target activated T-cells in the treatment of autoimmune diseases and inflammatory disorders.
According to the company, its research indicates that soluble Clever-1, secreted by Clever-1-positive macrophages and endothelial cells, binds to T-cells and impairs their differentiation into anti-tumour effectors.
Faron has identified the specific region of Clever-1 that interacts with T-cells, inactivating them. This new patent covers both soluble Clever-1 and its fragments for potential therapeutic applications in autoimmune diseases.
The company plans to develop an optimal drug composition from this discovery, aiming to expand its pipeline beyond oncology, which currently focuses on haematological cancers and solid tumours.
Galmed reveals novel pharmacodynamic blood markers for Aramchol SCD1 inhibitor
Evommune initiates EVO756 Phase 2b trial in adults with chronic spontaneous urticaria
Telix Pharmaceuticals' TLX101 glioma therapy candidate shows promising efficacy
FluoGuide begins phase II trial of FG001 for head and neck cancer
Sanofi advances respiratory pipeline with positive amlitelimab data and expanded clinical programmes
Intas and Accord BioPharma complete acquisition of UDENYCA (pegfilgrastim-cbqv) business
Sumitomo Pharma America signs research and development agreement with NCI
IDEAYA Biosciences advances Phase 3 design for darovasertib in primary uveal melanoma
Scancell partners with NHS Cancer Vaccine Launch Pad to accelerate melanoma trial recruitment
Sichuan Kelun-Biotech reveals sacituzumab tirumotecan (sac-TMT) clinical studies results
Amgen's IMDELLTRA shows superior overall survival in small cell lung cancer trial
EDX Medical launches new testicular cancer detection test in UK
Oncolytics Biotech signs share purchase agreement with Alumni Capital