Policy & Regulation
Charles River Launches Helper Plasmid to Streamline Adeno-Associated Viral Vector Manufacturing
15 March 2023 - - US-based Charles River Laboratories International, Inc. (NYSE: CRL) has launched its off-the-shelf pHelper offering, which is designed to secure supply and streamline adeno-associated virus -based gene therapy programs from early discovery through commercial manufacturing, the company said.

It is available immediately in Research Grade, High Quality, and Good Manufacturing Practice -grade.

Helper plasmids are the latest in a comprehensive collection of contract development and manufacturing organization products and services developed to simplify complex supply chains and safeguard viral vector packaging in cell and gene therapy programs.

This plasmid product is reliably manufactured and released with Chemistry, Manufacturing and Controls information and a certificate of Analysis to support regulatory filings and approval applications.

Charles River will officially launch its ready-to-use, off-the-shelf helper plasmid offering during an invite-only showcase event on March 13, Gene Therapy Spotlight: Investment, Regulatory and Development Perspectives, held in conjunction with the Advanced Therapies Congress, London, UK.