The fund raising was upsized and was led by Fidelity Management and Research company with participation from both new and existing investors, including Redmile Group, Invus, MiraeAsset Financial Group, Platinum Asset Management, Jebsen Capital, Steam Athena Capital, BVCF Management and the Struengmann Family Office.
Two-thirds of the funding came from new investors.
The proceeds of the financing will support the continued advancement of BioNTech's therapeutics pipeline and manufacturing infrastructure.
The funding follows the series A financing of USD 270m announced in January 2018, led by Redmile Group.
The previous financings have enabled BioNTech to advance a pipeline of seven product candidates in eight ongoing clinical trials, to establish a second GMP manufacturing license for production of its individualised neoantigen specific immunotherapies and to expand its antibody platform, most recently, through the acquisition of a Phase I/IIa programme against pancreatic cancer from MabVax Therapeutics Inc.
In conjunction with the MabVax Therapeutics acquisition of assets, the company has also recently established its US research and development facility in San Diego, California.
BioNTech was founded in 2008 on the understanding that every cancer patient's tumor is unique and therefore each patient's treatment should be individualised.
Its pipeline includes individualized mRNA-based product candidates, innovative chimeric antigen receptor T cells, novel checkpoint immunomodulators, targeted cancer antibodies and small molecules.
BioNTech's product development approach has been validated by seven collaborations with, in chronological order, Eli Lilly and company, Genmab, Sanofi, Bayer Animal Health, Genentech, a member of the Roche Group, Genevant and Pfizer, and its scientific approach through over 150 peer-reviewed scientific publications.
BioNTech's shareholders include the Struengmann Family Office as its majority shareholder, Fidelity Management and Research company, Invus, Janus Henderson Investors, MIG Fonds, Redmile Group, Salvia and several European family offices.
Natera submits Signatera CDx PMA to FDA for bladder cancer use
Astrazeneca Imfinzi perioperative regimen gains positive EU CHMP opinion in early gastric cancer
I Peace generates human iPS cells from NKT cells and offers them for research use
Frontage expands early phase clinical research capabilities across US and China
Summit Therapeutics' BLA for ivonescimab in EGFR-mutated NSCLC accepted by FDA
InSysBio agrees new collaborative project with BeOne Medicines
Physiomics secures new modelling contract with Numab Therapeutics
Mabwell reports first patient dosed with 7MW4911 in US trial
Atossa Therapeutics' founder and CEO named one of The Top 50 Healthcare Technology CEOs of 2025
Avacta secures FDA clearance for second pre|CISION oncology programme
Guardant Health and Merck enter multi-year oncology diagnostics collaboration
Akeso secures NMPA review acceptance for gumokimab in ankylosing spondylitis