Therapy Areas: Inflammatory Diseases
Hoth Therapeutics granted US patent for novel exon-skipping therapy targeting allergic diseases
13 February 2026 -

US biopharmaceutical company Hoth Therapeutics Inc (NASDAQ:HOTH) announced on Thursday that the United States Patent and Trademark Office (USPTO) has issued a Notice of Allowance for 'Exon Skipping of FC-Epsilon-RI-Beta and MS4A6A in the Treatment of Allergic Diseases'.

The Notice of Allowance confirms that the USPTO has allowed all pending claims in the application, moving the patent toward formal issuance.

This patent protects a novel dual-mechanism approach targeting key regulators of allergic and inflammatory responses.

The allowed claims cover methods directed at: exon skipping, a critical component of the high-affinity IgE receptor pathway central to allergic disease activation; modulation of MS4A6A, a gene associated with immune signalling and inflammatory regulation; and combination therapeutic strategies designed to reduce hypersensitivity responses at a molecular level.

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