Scottish gene control specialist Synpromics Ltd has entered into a collaborative agreement with University College London (UCL) to develop a gene therapy for Parkinson's disease, the company announced on Tuesday.
The pair will work to create an array of synthetic, novel gene promoters for the central nervous system (CNS), with the aim of generating a gene therapy.
The gene promoters can theoretically specifically control the expression of therapeutic genes in different sub-populations of neurones. UCL hopes that they can be used to advance a gene therapy-based approach for the treatment of young-onset Parkinson's disease.
Commenting on the news, Dr Michael Roberts, founder and chief scientific officer of Synpromics, stated: "Tightly controlling the therapeutic gene is an essential element in the development of any successful gene therapy and Synpromics' technology offers the best means to achieve that control.
"This collaboration will allow the company to develop a gene therapy approach for a largely unmet clinical need, where tight gene control is an absolute requirement. It also gives us the opportunity to work with UCL, one of the few world-leading institutions actively developing novel gene-based therapies."
Silo Pharma regains compliance with Nasdaq minimum bid price
Lilly acquires 4E Therapeutics to advance non-opioid chronic pain treatment
Bayer receives FDA approval for AMBELVIST MRI contrast agent
Lynk Pharmaceuticals' partner Formation Bio doses first participant in BLKR201 Phase 1 trial
Verge Labs and Tenacia Biotechnology collaborate on advancing Tenacia's CNS pipeline
Lunai Bioworks completes USD20m preferred issuance to acquire CNS delivery and neurotherapeutic IP
Solvonis Therapeutics appoints Water Tower Research to strengthen US market positioning
Solvonis Therapeutics secures second US patent for PTSD compound series
Insilico Medicine and Tenacia expand AI-driven R&D collaboration
TheraCryf advances lead addiction programme to final preclinical stage
Collegium to acquire AZSTARYS from Corium Therapeutics
Sanofi's venglustat receives FDA Breakthrough Therapy designation for type 3 Gaucher disease
GenomOncology partners with WeTrials to support CNS cancer clinical trials
Genentech's fenebrutinib meets primary endpoint in pivotal Phase III study for multiple sclerosis
Gemma Biotherapeutics doses first parent in GB221 Phase 1/2 CHARISMA clinical trial