New research from the largest study of its kind details a more comprehensive look at outcomes for COVID-19 patients with AKI, including kidney recovery, the need for dialytic support and post-discharge care.
AKI is a sudden episode of kidney injury or damage, preventing waste from being filtered within the body and can often lead to death.
The outcomes data published in the American Journal of Kidney Disease is a retrospective analysis of electronic health records of 9,657 hospitalized COVID-19 patients between March 1 and April 27, 2020.
The study found that 39.9% (3,854 of 9,657 of patients) developed AKI. While 83.4% (3,216) of those patients did not need kidney replacement therapies, 51.7% (1,663/3,216) survived.
Importantly, the majority of these patients 74.1% saw recovery of kidney function at the time of discharge.
Of patients with AKI who required KRT and survived, 66.7% (72/108) recovered kidney function. In the remaining AKI-KRT patients, a third (36/108) did not have kidney recovery, of which 91.7% who had not previously needed dialysis left the hospitals needing ongoing dialysis care after COVID-19 and AKI.
The Feinstein Institutes for Medical Research is the research arm of Northwell Health, the largest health care provider and private employer in New York State.
Home to 50 research labs, 2,500 clinical research studies and 5,000 researchers and staff, the Feinstein Institutes raises the standard of medical innovation through its five institutes of behavioral science, bioelectronic medicine, cancer, health innovations and outcomes, and molecular medicine.
We make breakthroughs in genetics, oncology, brain research, mental health, autoimmunity, and are the global scientific leader in bioelectronic medicine a new field of science that has the potential to revolutionise medicine.
GSK releases decade-long data on Shingrix efficacy
GSK announces positive EAGLE-1 results for gepotidacin in gonorrhoea treatment
Boehringer Ingelheim reports strong growth in 2023 and accelerates late-stage pipeline
Charles River Laboratories launches AMAP to reduce animal testing reliance
PureTech completes enrollment in Phase 2b ELEVATE IPF trial for LYT-100
Cybin secures additional US patent for CYB003 breakthrough therapy programme
UroGen's UGN-103 IND accepted by FDA for bladder cancer treatment
Biophytis reinforces obesity IP with new patent application
MaaT Pharma reveals positive 18-month data for MaaT013 in GI-aGvHD
Fusion Antibodies plc secures contract for OptiPhage library development
Innate Pharma advances Sanofi-developed NK cell engager to Phase 2 for blood cancer patients