Policy & Regulation
European Molecular Biology Laboratory reveals one in four drugs affect human gut bacteria growth
16 April 2018 -

Researchers from the European Molecular Biology Laboratory (EMBL) have revealed that one in four drugs with human targets is likely to affect the growth of bacteria in the human gut, it was reported on Friday.

In a Nature Microbiology paper, the researchers revealed that more than a quarter of the non-antibiotics restrict the growth of around one species in the microbiome. The work was conducted by the EMBL research group, including Peer Bork, Kiran Patil, Nassos Typas and Georg Zeller. The drugs from all therapeutic classes, in addition to anti-infectives have inhibited the growth of different gut microbes.

According to the EMBL, the study also indicates the earlier unnoticed risk that consumption of non-antibiotic drugs are likely to promote antibiotic resistance, as the general resistance mechanisms of microbes to human-targeted drugs and to antibiotics seem to largely overlap. EMBL scientists also reported that gut bacteria can be developed on 19 different growth media with well-defined recipes.

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