Biopharmaceutical company Akeso Inc (HK:9926) announced on Thursday that the first patient has been enrolled in the Phase I clinical trial of AK138D1 for the treatment of advanced malignancies in Australia.
AK138D1 is a self-developed and differentiated HER3-targeting ADC (antibody-drug conjugate), and is the company's first ADC drug to enter clinical studies.
Akeso's self-developed, first-in-class bispecific antibodies, cadonilimab (PD-1/CTLA-4) and ivonescimab (PD-1/VEGF), have both received regulatory approval and are now available to patients in China.
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